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ADA / Adenosine Deaminase

adenosine deaminase

Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.

Gene Name:	adenosine deaminase
Synonyms:	ADA, Adenosine deaminase, ADA1, Adenosine aminohydrolase
Target Sequences:	NM_000022 NP_000013.2 P00813

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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