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ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
| Gene Name: | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| Synonyms: | ACTR1B, Actin-related protein 1B, Beta-centractin, Centractin beta, PC3, ARP1B, CTRN2 |
| Target Sequences: | NM_005735 NP_005726.1 P42025 |
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