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ACTL7B

actin-like 7B

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.

Gene Name: actin-like 7B
Synonyms: ACTL7B, Actin-like protein 7B, Actin-like-7-beta, Actin-like 7-beta, Actin-like 7B, Tact1
Target Sequences: NM_006686 NP_006677.1 Q9Y614

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
ACTL7B (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
ACTL7B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ACTL7B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.1 kDa
100 µg/$494
ACTL7B Protein - 12.5% SDS-PAGE of human ACTL7B stained with Coomassie Blue
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Wheat Germ Extract
GST
71.6 kDa
10 µg/$479; 25 µg/$670
ACTL7B Protein - Purified recombinant protein ACTL7B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.1 kDa
20 µg/$1,107
ACTL7B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.1 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).