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ACS5 / ACSL5
acyl-CoA synthetase long-chain family member 5
Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
| Gene Name: | acyl-CoA synthetase long-chain family member 5 |
| Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
| Synonyms: | ACSL5, ACS2, ACS5, FACL5, Fatty acid coenzyme A ligase 5, Phosphatidylinositol 4-kinase, LACS 5 |
| Target Sequences: | NM_016234 NP_057318.2 Q9ULC5 |
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