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ACOX1 / ACOX

acyl-CoA oxidase 1, palmitoyl

Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.

Gene Name:	acyl-CoA oxidase 1, palmitoyl
Synonyms:	ACOX1, ACOX, Acyl-CoA oxidase 1, palmitoyl, Acyl-coa oxidase, peroxisomal, AOX, SCOX, PALMCOX, Palmitoyl-CoA oxidase
Target Sequences:	NM_004035 NP_004026.2 Q15067

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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