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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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ACOT7 / BACH
acyl-CoA thioesterase 7
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl-CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.
| Gene Name: | acyl-CoA thioesterase 7 |
| Synonyms: | ACOT7, ACH1, Acyl-CoA thioesterase 7, Acyl-CoA thioesterase 2, Brain acyl CoA hydrolase, Brain acyl-CoA hydrolase, CTE-II, HBACH, LACH1, LACH, RP1-120G22.10, BACH, CTE-IIa |
| Target Sequences: | NM_007274 NP_009205.3 O00154 |
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