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ACOT11 / THEA
acyl-CoA thioesterase 11
ACOT11 / THEA is a member of the acyl-CoA thioesterase family which catalyse the conversion of activated fatty acids to the corresponding non-esterified fatty acid and coenzyme A. Expression of a mouse homolog in brown adipose tissue is induced by low temperatures and repressed by warm temperatures. Higher levels of expression of the mouse homolog has been found in obesity-resistant mice compared with obesity-prone mice, suggesting a role of acyl-CoA thioesterase 11 in obesity. Alternative splicing results in transcript variants.
| Gene Name: | acyl-CoA thioesterase 11 |
| Synonyms: | ACOT11, BFIT2, Acyl-CoA thioesterase 11, KIAA0707, STARD14, THEM1, START domain containing 14, THEA, BFIT, BFIT1 |
| Target Sequences: | AK023937 BAB14734.1 Q8WXI4 |
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