ACE2 / ACE-2

angiotensin I converting enzyme 2

Angiotensin-Converting Enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function. ACE2 is also the attachment receptor for HCoV-N63, SARS-CoV and SARS-CoV-2. The S1 portion of the coronavirus spike protein attaches to ACE2 presented on the host cell surface. The SARS-CoV-2 virus targets pneumocytes and macrophages expressing ACE2 in the lung, and it is believed to infect ACE2-positive cells in other tissues including the gastrointestinal tract and potentially the liver (in cholangiocytes).

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Products

ELISA Kits (26)

Type

Competitive EIA (2)

Custom (2)

Sandwich (21)

Sandwich CLIA (1)

Target

ACE2 / ACE-2 (26)

Reactivity

Human (8)

Mouse (6)

Rat (6)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Product Group

Coronavirus Detection (26)

ELISA Kits for Associated Targets (26)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (3)

96-Well Strip Plate (22)

Publications

No (25)

Yes (1)

Sample Type

Cell Culture Supernatants (6)

Cell Lysates (1)

Plasma (21)

Serum (21)

Tissue Homogenates (6)

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Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F22457

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.39 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F5886

(4.0) Rating

(1) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.63 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$537

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Rat ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F5059

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$856

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Mouse ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F7614

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F24345

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

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Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F10722

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Rat ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F10723

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F54559

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

6.25 - 400 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

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Rat ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F33787

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$768

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Monkey ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F41125

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Porcine ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F41127

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.391 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F24709

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

Select

Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F51410

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$870

Select

Chicken ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F41124

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Guinea pig ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F41126

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Rabbit ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F41128

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

Select

Rat ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F53635

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 IU/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Rat ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F22380

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

Select

Mouse ACE2 / ACE-2 (Custom ELISA) ELISA Kit - LS-F18727

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Bovine ACE2 / ACE-2 (Custom ELISA) ELISA Kit - LS-F18728

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F33788

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.391 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat ACE2 / ACE-2 (Competitive EIA) ELISA Kit - LS-F27856

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Human ACE2 / ACE-2 (CLIA) ELISA Kit - LS-F29275

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

78.125 - 5000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

Select

Mouse ACE2 / ACE-2 (Competitive EIA) ELISA Kit - LS-F28162

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

250 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

Select

Human ACE2 / ACE-2 (Sandwich ELISA) ELISA Kit - LS-F26657

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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