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ABHD5
abhydrolase domain containing 5
ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
| Gene Name: | abhydrolase domain containing 5 |
| Synonyms: | ABHD5, CDS, CGI-58, IECN2, NCIE2, CGI58 |
| Target Sequences: | NM_016006 NP_057090.2 Q8WTS1 |
Publications (3)
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