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ABCD4

ATP-binding cassette, sub-family D (ALD), member 4

ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

Gene Name: ATP-binding cassette, sub-family D (ALD), member 4
Family/Subfamily: Transporter , ATP-binding cassette - ABCD/ALD
Synonyms: ABCD4, ABC41, EST352188, p70R, PMP70-related protein, MAHCJ, p79R, PMP69, PXMP1-L, PXMP1L
Target Sequences: NM_005050 NP_005041.1 O14678

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
ABCD4 (5)
No (5)
His-T7, N-terminus (2)
Myc-DDK (Flag) (3)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
ABCD4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68.4 kDa
100 µg/$494
ABCD4 Protein - Purified recombinant protein ABCD4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
68.4 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
68.4 kDa
20 µg/$150
ABCD4 Protein - Recombinant ATP Binding Cassette Transporter D4 (ABCD4) by SDS-PAGE
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E. coli
His-T7, N-terminus
31.6kDa
10 µg/$269; 50 µg/$365; 200 µg/$730; 100 µg/$582; 1 mg/$1,766; 500 µg/$1,335; 5 mg/$2,722; 2 mg/$1,947
ABCD4 Protein - Recombinant ATP Binding Cassette Transporter D4 (ABCD4) by SDS-PAGE
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E. coli
His-T7, N-terminus
31.6kDa
10 µg/$274; 50 µg/$395; 200 µg/$790; 100 µg/$632; 1 mg/$1,858; 500 µg/$1,414; 5 mg/$2,820; 2 mg/$2,041
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).