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ABCC8 / SUR1

ATP-binding cassette, sub-family C (CFTR/MRP), member 8

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not yet been fully described.

Gene Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Family/Subfamily: Transporter , ATP-binding cassette - ABCC/MRP
Synonyms: ABCC8, ABC36, HI, PHHI, Sulfonylurea receptor, SUR, Sulfonylurea receptor 1, MRP8, SUR1delta2, HHF1, HRINS, SUR1, TNDM2
Target Sequences: NM_000352 NP_000343.2 Q09428

Filtered By: None
Target
abcc8-sur1 (31)
Reactivity
Human (12)
Mouse (23)
Rat (24)
Bat (4)
Bovine (5)
Dog (1)
Hamster (18)
Horse (1)
Monkey (4)
Pig (4)
Rabbit (4)
Application
IHC (20)
IHC-P (4)
WB (28)
ELISA (4)
ICC (20)
Host
rabbit (11)
mouse (19)
goat (1)
Isotype
IgG (6)
IgG1 (18)
IgG1,k (1)
Clonality
monoclonal mc (19)
polyclonal pc (12)
Clone
3E1 (1)
S289-16 (18)
Format
AP Conjugated (1)
APC Conjugated (1)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 565 Conjugated (1)
Atto 594 Conjugated (2)
Atto 633 Conjugated (1)
Atto 655 Conjugated (1)
Atto 680 Conjugated (1)
Atto 700 Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (1)
PE (1)
PerCP Conjugated (1)
RPE Conjugated (1)
SA Conjugated (1)
Unconjugated (10)
Epitope
aa1548-1582 (17)
N-Terminus (4)
aa679-929 (3)
aa1559-1571 (1)
Publications
No (31)
Showing 1-25 out of 31 results
Anti-ABCC8 / SUR1 Antibody (N-Terminus) IHC-plus™ LS-B5774

Rabbit Polyclonal to Human ABCC8 / SUR1
Rabbit, Mouse, Bovine, Rat, Pig, Bat, Human, Monkey
IHC-P WB
Unconjugated
Anti-ABCC8 / SUR1 Antibody (clone S289-16) LS-C150482

Mouse Monoclonal [clone S289-16] (IgG1)
Mouse, Rat, Hamster
ICC IHC WB
Unconjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Biotin) LS-C231736

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Biotin Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, FITC) LS-C231735

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
FITC Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 390) LS-C231725

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 390 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 488) LS-C231726

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 488 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 565) LS-C231727

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 565 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 594) LS-C231728

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 594 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 633) LS-C231729

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 633 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 655) LS-C231730

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 655 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 680) LS-C231731

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 680 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, AP) LS-C231732

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
AP Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, Atto 700) LS-C231733

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Atto 700 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, APC) LS-C231734

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
APC Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, PE, Atto 594) LS-C231738

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
PE, Atto 594 Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, PerCP) LS-C231739

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
PerCP Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, RPE) LS-C231740

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
RPE Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16, SA) LS-C231741

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
SA Conjugated
Anti-ABCC8 / SUR1 Antibody (aa1548-1582, clone S289-16) LS-C309133

Mouse Monoclonal [clone S289-16] (IgG1) to Rat ABCC8 / SUR1
Mouse, Rat, Hamster
ICC IHC WB
Unconjugated
Anti-ABCC8 / SUR1 Antibody LS-C403622

Rabbit Polyclonal (IgG) to Human ABCC8 / SUR1
Rat, Human
ELISA IHC
Unconjugated
Anti-ABCC8 / SUR1 Antibody LS-C406859

Rabbit Polyclonal (IgG) to Human ABCC8 / SUR1
Rat, Human
ELISA IHC
Unconjugated
Anti-ABCC8 / SUR1 Antibody (clone 3E1) LS-C139460

Mouse Monoclonal [clone 3E1] (IgG1,k) to Human ABCC8 / SUR1
Human
ELISA WB
Unconjugated
Anti-ABCC8 / SUR1 Antibody (aa1559-1571) LS-C112763

Goat Polyclonal to Human ABCC8 / SUR1
Dog, Bovine, Horse, Human
ELISA WB
Unconjugated
Anti-ABCC8 / SUR1 Antibody (aa679-929, Biotin) LS-C423251

Rabbit Polyclonal (IgG) to Human ABCC8 / SUR1
Human
ICC WB
Biotin Conjugated
Anti-ABCC8 / SUR1 Antibody (aa679-929, FITC) LS-C423253

Rabbit Polyclonal (IgG) to Human ABCC8 / SUR1
Human
ICC WB
FITC Conjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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