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ABCB7

ATP-binding cassette, sub-family B (MDR/TAP), member 7

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 7
Family/Subfamily: Transporter , ATP-binding cassette - ABCB/MDR
Synonyms: ABCB7, ABC transporter 7 protein, ABC7, Atm1p, ATP-binding cassette 7, ASAT, EST140535
Target Sequences: NM_004299 BAA28861.1 O75027

Publications (1)

1
Exploring the mechanistic link between SF3B1 mutation and ring sideroblast formation in myelodysplastic syndrome. Tetsuro Ochi, Tohru Fujiwara, Koya Ono, Chie Suzuki, Maika Nikaido, Daichi Inoue, Hiroki Kato, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Hideo Harigae. Scientific reports. 2022 August;12:14562. [Full Text Article] [PubMed:36028755] [PMC:PMC9418223] Related Antibodies: LS-B13035.

☰ Filters
Antibodies (46)
Proteins (5)
Over-Expression Lysate (2)
Primary (46)
Recombinant (3)
ABCB7 (51)
Human (37)
Mouse (15)
Rat (6)
Chicken (3)
Chimpanzee (3)
Dog (3)
Drosophila (3)
Hamster (3)
Monkey (3)
IHC (18)
IHC-P (4)
WB (40)
ELISA (7)
IF (2)
IP (1)
Peptide-ELISA (3)
rabbit (45)
rabbit-new zealand white (1)
Product Group
IHCPlus (2)
IgG (18)
polyclonal pc (46)
APC (2)
APC Conjugated (3)
Biotin Conjugated (6)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (3)
Unconjugated (18)
aa718-746 (7)
C-Terminus (5)
aa593-642 (4)
660-740 aa, C-terminal (1)
aa680-729 (1)
aa691-740 (1)
aa707-752 (1)
No (50)
Yes (1)
GST (1)
His-T7, N-terminus (2)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
ABCB7 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ABCB7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ABCB7 Antibody - Immunohistochemistry of paraffin-embedded human liver using ABCB7 antibody at dilution of 1:100 (40x lens).
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ABCB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
ABCB7 Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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ABCB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ABCB7 Antibody - Western blot of ABCB7 antibody
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ABCB7 Rabbit anti-Human Polyclonal (660-740 aa, C-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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ABCB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IP, WB
Unconjugated
100 µg/$331
ABCB7 Antibody - Anti-ABCB7 antibody IHC of human lung, alveoli. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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ABCB7 Rabbit anti-Human Polyclonal (aa691-740) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
Select
ABCB7 Rabbit anti-Human Polyclonal (aa718-746) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
ABCB7 Rabbit anti-Human Polyclonal (aa718-746) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
ABCB7 Rabbit anti-Human Polyclonal (aa718-746) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
ABCB7 Rabbit anti-Human Polyclonal (aa718-746) (FITC) Antibody
Human
IHC, WB
FITC Conjugated
200 µl/$952
Select
ABCB7 Rabbit anti-Human Polyclonal (aa718-746) (APC) Antibody
Human
IHC, WB
APC Conjugated
200 µl/$952
Select
ABCB7 Rabbit anti-Human Polyclonal (aa718-746) (PE) Antibody
Human
IHC, WB
PE Conjugated
200 µl/$952
ABCB7 Antibody - Immunohistochemistry image of paraffin-embedded human pancreatic cancer at a dilution of 1:100
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ABCB7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
ABCB7 Antibody - Western blot analysis of the lysates from HUVECcells using ABCB7 antibody.
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ABCB7 Rabbit anti-Human Polyclonal (aa680-729) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
ABCB7 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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ABCB7 Rabbit anti-Human Polyclonal (aa718-746) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Select
ABCB7 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
100 µl/$393
Select
ABCB7 Rabbit anti-Human Polyclonal (aa707-752) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
ABCB7 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ABCB7 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human thymus gland tissue using ABCB7 antibody.
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ABCB7 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$357
ABCB7 Antibody - Western Blot; Sample: Recombinant protein.
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ABCB7 Rabbit anti-Mouse Polyclonal Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
ABCB7 Antibody - Western Blot; Sample: Recombinant protein.
Select
ABCB7 Rabbit anti-Mouse Polyclonal (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
ABCB7 Antibody - Western Blot; Sample: Recombinant protein.
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ABCB7 Rabbit anti-Mouse Polyclonal (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
ABCB7 Antibody - Western blot of Human COLO205. ABCB7 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB7 Rabbit anti-Human Polyclonal (aa593-642) Antibody
Human
WB
Unconjugated
100 µl/$424
ABCB7 Antibody - Western blot of ABCB7 Antibody with HeLa Whole cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ABCB7 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
ABCB7 Antibody
Select
ABCB7 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
Viewing 1-25 of 51 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).