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ABCB6

ATP-binding cassette, sub-family B (MDR/TAP), member 6

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

Gene Name: ATP-binding cassette, sub-family B (MDR/TAP), member 6
Family/Subfamily: Transporter , ATP-binding cassette - ABCB/MDR
Synonyms: ABCB6, ABC14, ABC, EST45597, LAN, MTABC3, PrP, P-glycoprotein-related protein, MCOPCB7, Mt-ABC transporter 3, Umat
Target Sequences: AJ289233 AAH00559.1 Q9NP58

Publications (1)

1
Classification of subcellular location by comparative proteomic analysis of native and density-shifted lysosomes. Della Valle MC, Sleat DE, Zheng H, Moore DF, Jadot M, Lobel P. Molecular & cellular proteomics : MCP. 2011 10:M110.006403. (WB; Rat) [Full Text Article] [PubMed:21252268] [PMC:PMC3069348] Related Antibodies: LS-C19004.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
ABCB6 (4)
No (4)
GST, N-terminus (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
ABCB6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
ABCB6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
93.7 kDa
100 µg/$494
ABCB6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
93.7 kDa
20 µg/$150
ABCB6 Protein - Recombinant ATP Binding Cassette Transporter B6 (ABCB6) by SDS-PAGE
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E. coli
His-T7, N-terminus
31.1kDa
10 µg/$269; 50 µg/$367; 200 µg/$732; 100 µg/$587; 1 mg/$1,773; 500 µg/$1,340; 5 mg/$2,729; 2 mg/$1,952
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).