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ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import.
| Gene Name: | ATP-binding cassette, sub-family A (ABC1), member 9 |
| Family/Subfamily: | Transporter , ATP-binding cassette - ABCA/ABC1 |
| Synonyms: | ABCA9, ATP-binding cassette A9, ABC-A9, EST640918 |
| Target Sequences: | NM_080283 NP_525022.2 Q8IUA7 |
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