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ABCA4

ATP-binding cassette, sub-family A (ABC1), member 4

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

Gene Name: ATP-binding cassette, sub-family A (ABC1), member 4
Family/Subfamily: Transporter , ATP-binding cassette - ABCA/ABC1
Synonyms: ABCA4, ABCR, ABC10, ARMD2, CORD3, FFM, RIM ABC transporter, RIM protein, RMP, RP19, STGD, Photoreceptor rim protein, Stargardt disease protein, STGD1
Target Sequences: NM_000350 NP_000341.2 P78363

☰ Filters
Antibodies (27)
ELISA Kits (4)
Proteins (2)
Primary (27)
Recombinant (2)
Sandwich (4)
ABCA4 (33)
Human (26)
Mouse (10)
Rat (5)
Bat (1)
Bovine (1)
Dog (1)
Guinea pig (1)
Monkey (2)
Rabbit (1)
Xenopus (1)
IHC (9)
IHC-P (6)
WB (22)
ELISA (3)
ICC (1)
IF (1)
Peptide-ELISA (3)
rabbit (21)
mouse (1)
goat (2)
rabbit-new zealand white (3)
Product Group
PathPlus Cancer (2)
IgG (7)
monoclonal mc (1)
polyclonal pc (26)
3F4 (1)
96-Well Microplate (1)
96-Well Strip Plate (3)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (20)
aa1398-1727 (8)
C-Terminus (1)
Internal (1)
aa1336-49 (1)
aa1892-1903 (1)
aa1893-1906 (1)
aa2230-2273 (1)
aa2250-2263 (1)
No (33)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (2)
Serum (2)
Tissue Homogenates (3)
GST, N-terminus (1)
His, N-Terminal (1)
Human (2)
E. coli (1)
Wheat Germ Extract (1)
Select
ABCA4 Goat anti-Human Polyclonal (aa2250-2263) Antibody
Human
ICC, IF, Peptide-ELISA
Unconjugated
100 µg/$503
ABCA4 Antibody - IHC of adult mouse retina showing specific immunolabeling of the ABCA4 protein. Photo courtesy of Mary Raven, University of California, Santa Barbara, CA
Select
ABCA4 Mouse anti-Bovine Monoclonal (3F4) Antibody
Xenopus, Mouse, Bovine, Human
IHC, WB
Unconjugated
100 µl/$469
ABCA4 Antibody - Western blot analysis of extracts of various cell lines, using ABCA4 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 10s.
Select
ABCA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ABCA4 Antibody - Western blot analysis of ABCA4 expression in HEK293T (A); NS-1 (B); PC12 (C) whole cell lysates.
Select
ABCA4 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Dog, Rat, Human, Monkey
WB
Unconjugated
100 µl/$299
ABCA4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$783
ABCA4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
ABCA4 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
ABCA4 ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
ABCA4 Antibody - Western Blot; Sample: Recombinant ABCA4, Human.
Select
ABCA4 Rabbit anti-Human Polyclonal (aa1398-1727) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
ABCA4 Antibody - Western Blot; Sample: Recombinant ABCA4, Human.
Select
ABCA4 Rabbit anti-Human Polyclonal (aa1398-1727) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
ABCA4 Antibody - Western Blot; Sample: Recombinant ABCA4, Human.
Select
ABCA4 Rabbit anti-Human Polyclonal (aa1398-1727) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Select
ABCA4 Goat anti-Human Polyclonal (aa1336-49) Antibody
Human
Peptide-ELISA
Unconjugated
100 µg/$401
ABCA4 Antibody - Human Retina: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Cancer
Fast Shipping
ABCA4 Rabbit anti-Human Polyclonal Antibody
IHC-P
Unconjugated
50 µg/$460
ABCA4 Antibody - Immunohistochemistry (IHC) analysis of ABCA4 antibody in paraffin-embedded human colon carcinoma tissue at 1:50, showing membrane staining. Negative control (the right) using PBS instead of primary antibody. Secondary antibody is Goat Anti-Rabbit IgG-biotin.
Select
ABCA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
ABCA4 Antibody - WB of ABCA4 antibody. All lanes: Anti-ABCA4 at 0.5ug/ml. WB: SHG Whole Cell Lysate at 40ug. Predicted bind size: 256KD. Observed bind size: 256KD.
Select
ABCA4 Rabbit anti-Human Polyclonal (aa1893-1906) Antibody
Human, Monkey
WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
ABCA4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$331
ABCA4 Antibody - Human Brain, Cortex
Select
Cancer
ABCA4 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µl/$460
ABCA4 Protein - Recombinant  ATP Binding Cassette Transporter A4 By SDS-PAGE
Select
E. coli
His, N-Terminal
40.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
ABCA4 Antibody - Western blot analysis of ABCA4 using HT29 whole cells lysates
Select
ABCA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ABCA4 Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using ABCA4 Polyclonal Antibody at dilution of 1:30.
Select
ABCA4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
ABCA4 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCA4 Rabbit-New Zealand White anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCA4 Rabbit-New Zealand White anti-Human Polyclonal (aa2230-2273) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
Select
ABCA4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
ABCA4 Antibody - Western blot testing of 1) rat eye and 2) mouse eye lysate with ABCA4 antibody at 0.5ug/ml. Predicted molecular weight ~256 kDa.
Select
ABCA4 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
100 µg/$575
Viewing 1-25 of 33 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).