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ABCA13

ATP-binding cassette, sub-family A (ABC1), member 13

In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.

Gene Name: ATP-binding cassette, sub-family A (ABC1), member 13
Family/Subfamily: Transporter , ATP-binding cassette - ABCA/ABC1
Synonyms: ABCA13
Target Sequences: NM_152701 NP_689914.3 Q86UQ4

Publications (1)

1
ABCA13 dysfunction associated with psychiatric disorders causes impaired cholesterol trafficking. Mitsuhiro Nakato, Naoko Shiranaga, Maiko Tomioka, Hitomi Watanabe, Junko Kurisu, Mineko Kengaku, Naoko Komura, Hiromune Ando, Yasuhisa Kimura, Noriyuki Kioka, Kazumitsu Ueda. The Journal of biological chemistry. 2020 December; [Full Text Article] [PubMed:33478937] [PMC:PMC7948424] Related Antibodies: LS-C373172.

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ABCA13 Protein - Recombinant  ATP Binding Cassette TransPorter A13 By SDS-PAGE
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E. coli
His-GST
56.1 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).