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AAGAB interacts with the gamma-adaptin and alpha-adaptin subunits of complexes involved in clathrin-coated vesicle trafficking. Mutations in this gene are associated with type I punctate palmoplantar keratoderma. Alternatively spliced transcript variants have been found for this gene.
Gene Name: | alpha- and gamma-adaptin binding protein |
Synonyms: | AAGAB, p34, PPKP1A, PPKP1, FLJ11506, KPPP1 |
Target Sequences: | NM_024666 NP_078942.3 Q6PD74 |
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