Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

A2M / Alpha-2-Macroglobulin

alpha-2-macroglobulin

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Gene Name: alpha-2-macroglobulin
Synonyms: A2M, CPAMD5, A2MD, FWP007, Alpha-2-M, Alpha-2-macroglobulin, S863-7
Target Sequences: NM_000014 NP_000005.2 P01023

☰ Filters
Products
Proteins (16)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (12)
A2M / Alpha-2-Macroglobulin (16)
No (16)
GST, N-terminus (1)
His (9)
His, N-Terminal (2)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Human (7)
Mouse (2)
Pig (1)
Rat (5)
293T Cells (1)
E. coli (8)
HEK 293 Cells (4)
Insect Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (1)
Low endotoxin level (1)
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
27.6 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
A2M / Alpha-2-Macroglobulin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
163.28 kDa
100 µg/$494
Select
HEK 293 Cells
His, N-Terminal
~161 kDa
100 µg/$298
Select
HEK 293 Cells
His, N-Terminal
~161 kDa
200 µl/$283
A2M / Alpha-2-Macroglobulin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
163.28 kDa
20 µg/$150
Select
Insect Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
164 kDa
50 µg/$721
A2M / Alpha-2-Macroglobulin Protein
Select
Yeast
His
16.9 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
Select
E. coli
His
35.6 kDa
10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252
A2M / Alpha-2-Macroglobulin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
A2M / Alpha-2-Macroglobulin Protein - Purified recombinant protein A2M was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
160.8 kDa
20 µg/$1,107
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
28.4 kDa
10 µg/$251; 50 µg/$311; 100 µg/$402; 200 µg/$502; 1 mg/$1,365; 500 µg/$1,002; 5 mg/$2,254; 2 mg/$1,523
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
19.7 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,489
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
30.6 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
26.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
19.5 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
A2M / Alpha-2-Macroglobulin Protein - Recombinant Alpha-2-Macroglobulin By SDS-PAGE
Select
E. coli
His
27.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
Viewing 1-16 of 16 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).