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A1CF / ACF

APOBEC1 complementation factor

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene Name: APOBEC1 complementation factor
Synonyms: A1CF, ACF65, ACF64, APOBEC-1 stimulating protein, APOBEC1 complementation factor, APOBEC1CF, ACF, Apo-B RNA editing protein, APOBEC1-stimulating protein, RP11-564C4.2, ASP
Target Sequences: NM_014576 NP_055391.2 Q9NQ94

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A1CF / ACF ELISA Kit
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31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).