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TDO2 Protein (Recombinant His) (Full Length) - LS-G4006

Catalog Size Price
LS-G4006-50 50 µg Unavailable
LSBio (USA Sales Only) LSBio (USA Sales Only)

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100% Guaranteed
Recombinant Protein
~47.9kDa Full Length
Full-length TDO (Anopheles gambiae) is fused at the N-terminus to a His-tag.
E. coli
E. coli
Greater than 98% by SDS-PAGE
Specific activity towards L-Trp: 87.0µmol/hr per mg. TDO catalyzes the oxidative opening of the L-tryptophan indole moiety to yield N-formylkynurenine (NFK).
Not Tested
50 mM sodium phosphate, pH 8.0, 0.15 M NaCl, 0.2 M imidazole, 10% glycerol
Store at +4°C for immediate use, or aliquot and store at -80°C for at least 6 months. Avoid repeat freeze-thaw cycles.
For research use only.

About TDO2

P48775 NM_005651 NP_005642.1

TDO2 Protein, TDO Protein, TO Protein, TRPO Protein, Tryptophan pyrrolase Protein, Tryptophan oxygenase Protein, Tryptophan 2,3-dioxygenase Protein, Tryptophanase Protein, Tryptamin 2,3-dioxygenase Protein

TDO2 is a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Requested From: 
Date Requested: 4/20/2018

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