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RPS6KB1 / P70S6K / S6K Recombinant Protein - LS-G5453

LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular RPS6KB1 / P70S6K / S6K Proteins

RPS6KB1 / P70S6K / S6K Recombinant Protein - LS-G5453
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Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).

100% Guaranteed
LS-G5453
Recombinant Protein
RPS6KB1 / P70S6K / S6K
76.0 kDa
Sf21 Cells
Spodoptera frugiperda
None
Greater than 90% by SDS-PAGE
132 nmol phosphate incorporated into S6K substrate peptide per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 µM ATP (0.83 µCi/assay).
Not Tested
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About RPS6KB1 / P70S6K / S6K

P23443 NM_003161 NP_003152.1

RPS6KB1 Protein, 70 kDa S6 kinase Protein, p70 S6KA Protein, p70-alpha Protein, p70-S6K Protein, p70 S6 kinase alpha Protein, p70s6 kinase Protein, S6K-beta-1 Protein, STK14A Protein, p70 ribosomal S6 kinase Protein, p70 S6 kinase, alpha 1 Protein, p70 S6 kinase, alpha 2 Protein, p70 S6K-alpha Protein, p70-S6K 1 Protein, p70S6K Protein, p70S6K1 Protein, PS6K Protein, Ribosomal protein S6 kinase I Protein, S6K Protein, S6K1 Protein, p70 ribosomal S6 kinase alpha Protein, p70(S6K)-alpha Protein

Serine/threonine-protein kinase that acts downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression. Regulates protein synthesis through phosphorylation of EIF4B, RPS6 and EEF2K, and contributes to cell survival by repressing the pro-apoptotic function of BAD. Under conditions of nutrient depletion, the inactive form associates with the EIF3 translation initiation complex.

Requested From: 
Date Requested: 6/24/2017

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