Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
CABP9K (CALB3 or CABP1; mouse, rat, and human 79 aa; chromosome Xp; ~9 kDa) is a cytosolic Ca-binding protein initially found in rat pancreas. It is also expressed in intestine, placenta, uterus and kidney. Its expression is controlled by vitamin D and sex hormone in a tissue specific manner. In keeping with its role in Ca-transport, its expression is highest in duodenal villus enterocytes. It is further shown that CABP9K is only expressed in differentiated enterocytes. CABP9K gene also contains Cdx2-homeoprotein binding sites, and that Cdx2 may play a crucial role in CABP9K transcription.CaBP9K is expressed with a -6xHis tag and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
Lyophilized from 100 mM Phosphate buffer, pH 7.3.
Store at -20°C lyophilized. Once reconstituted, aliquot to avoid freeze/thaw and store at -20°C.
S100G Protein, CABP Protein, S100 calcium-binding protein G Protein, Protein S100-G Protein, S100D Protein, CABP9K Protein, CALB3 Protein, Calbindin D9K Protein, Calbindin-D9K Protein, S100 calcium binding protein G Protein
Calbindin D9K, the vitamin D-dependent calcium-binding protein (CALB3) is a cytosolic protein of molecular weight 9000 and belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. CALB3 is found in the mammalian intestine, placenta, uterus, and kidney. Its exact function is unknown. The intestinal protein is vitamin D-dependent and its expression correlates with calcium transport activity.