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Rat GRN / Granulin Recombinant (FLAG) Protein LS-G3864


Wt. Vol. Conc. Price
10 µg - - $255
50 µg - - $375
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

Most Popular GRN / Granulin Proteins

Mouse GRN / Granulin Recombinant Protein - LS-G4543
Human HEK 293 Cells
Unpurified / Endotoxin Level: Less than 0.1 EU/µg protein.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human GRN / Granulin Recombinant Protein - LS-G4550
Human HEK 293 Cells
Unpurified / Lyophilized
Rat GRN / Granulin Recombinant Protein - LS-G4551
Human HEK 293 Cells
Unpurified / Endotoxin Level: Less than 0.1 EU/µg protein.
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
Recombinant Protein
GRN / Granulin
~65kDa (SDS-PAGE)
Signal peptide and rat progranulin (aa 1-602) are fused at the C-terminus to a FLAG®-tag.
aa 1-602
HEK 293 Cells
Greater than 95% by SDS-PAGE
Less than 0.1 EU/µg protein (determined by LAL method).
Lyophilized from PBS.
Store lyophilized at -20°C for at least 1 year. Once reconstituted store at +4°C for immediate use.
For research use only.

About GRN / Granulin

P28799 NM_002087 NP_002078.1

GRN Protein, Acrogranin Protein, CLN11 Protein, Epithelin precursor Protein, GEP Protein, gp88 Protein, Granulin Protein, Granulin-epithelin Protein, Granulins Protein, PC cell-derived growth factor Protein, PCDGF Protein, PEPI Protein, PGRN Protein, Proepithelin Protein, Progranulin Protein

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc.

Functional Assay

Functional Assay
Deglycosylation of rat progranulin. To examine the deglycosylation of rat Progranulin-FLAG, 1 ug of rat progranulin is denatured with 1X glycoprotein denaturing buffer at 100 degrees C for 10 minutes. After the addition of NP-40 and G7 reaction buffer, two-fold dilutions of PNGase F are added and the reaction mix is incubated for 1 or 3 hours at 37 degrees C. Separation of reaction products is visualized by immunoblotting using anti-FLAG-HRP antibody.

Functional Assay

Functional Assay
NH2-terminal sequence analysis.

Requested From: United States
Date Requested: 10/24/2016

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