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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Catalog Number Size Price
LS-G3910-10 10 µg (0.1 mg/ml) $315 
Protein

Human TNFSF10 / TRAIL Protein (Recombinant Isoleucine zipper motif) (aa95-281) - LS-G3910

Human TNFSF10 / TRAIL Protein (Recombinant Isoleucine zipper motif) (aa95-281) - LS-G3910

Description:
TNFSF10 / TRAIL Protein LS-G3910 is Recombinant Human TNFSF10 / TRAIL aa 95-281 produced in E. coli with Isoleucine zipper motif tag(s). It is biologically active and is low in endotoxin Less than 0.01 EU/µg protein (determined by LAL method)..
Price
Catalog Number
$315 
LS-G3910-10
10 µg
0.1 mg/ml
Toll Free North America
866-819-4732

Overview

Description:
TNFSF10 / TRAIL Protein LS-G3910 is Recombinant Human TNFSF10 / TRAIL aa 95-281 produced in E. coli with Isoleucine zipper motif tag(s). It is biologically active and is low in endotoxin Less than 0.01 EU/µg protein (determined by LAL method)..

Specifications

Type
Recombinant Protein
Target
TNFSF10 / TRAIL
Species
Human
Modifications
Unmodified
Predicted Molecular Weight
28kDa-82kDa
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 95% by SDS-PAGE
Bio-Activity
Induces apoptosis in vitro in different human cancer cell lines with an EC50 of 5-200ng/ml, depending on the individual cell line used. Recombinant izTRAIL does not kill 4-day cultures of primary human hepatocytes (PHH) at concentrations of at least up to 1µg/ml (Ganten 2006). Good bioavailability in vivo, shows no toxic effects in mice at doses of at least up to 500µg per day (Wissink 2006).
Endotoxin
Less than 0.01 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 20 mM Tris-Cl, 0.5 M Arginine-HCl, 100 mM NaCl, 0.02% Tween20
Reconstitution
Reconstitute with 100 µl sterile water.
Storage
Store lyophilized at -20°C for up to 6 months. Once reconstituted store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
Guarantee
This protein carries the LSBio 100% Guarantee.
LSBio Guarantee
About TNFSF10 / TRAIL
P50591 NM_003810 NP_003801.1

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Requested From: United States
Date Requested: 11/12/2019