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| Catalog Number | Size | Price |
|---|---|---|
| LS-G3910-10 | 10 µg | $337 |
Human TNFSF10 / TRAIL Protein (Recombinant Isoleucine Zipper Motif) (aa95-281) - LS-G3910
Human TNFSF10 / TRAIL Protein (Recombinant Isoleucine Zipper Motif) (aa95-281) - LS-G3910
Description:
TNFSF10 / TRAIL Protein LS-G3910 is a Recombinant Human TNFSF10 / TRAIL produced in E. coli aa 95-281 with Isoleucine Zipper Motif tag(s). It is biologically active and is low in endotoxin; Less than 0.01 EU/µg protein (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
TNFSF10 / TRAIL Protein LS-G3910 is a Recombinant Human TNFSF10 / TRAIL produced in E. coli aa 95-281 with Isoleucine Zipper Motif tag(s). It is biologically active and is low in endotoxin; Less than 0.01 EU/µg protein (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TNFSF10 / TRAIL
Synonyms
TNFSF10 | Apo-2L | APO2L | Apo-2 ligand | CD253 | CD253 antigen | TRAIL | Protein TRAIL | TL2
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Tag
Isoleucine Zipper Motif
Region
aa 95-281
Predicted Molecular Weight
28kDa-82kDa
Expression System
E. coli
Source Species
E. coli
Purification
Greater than 95% by SDS-PAGE
Bio-Activity
Induces apoptosis in vitro in different human cancer cell lines with an EC50 of 5-200ng/ml, depending on the individual cell line used. Recombinant izTRAIL does not kill 4-day cultures of primary human hepatocytes (PHH) at concentrations of at least up to 1µg/ml (Ganten 2006). Good bioavailability in vivo, shows no toxic effects in mice at doses of at least up to 500µg per day (Wissink 2006).
Endotoxin
Less than 0.01 EU/µg protein (determined by LAL method).
Presentation
Lyophilized from 20 mM Tris-Cl, 0.5 M Arginine-HCl, 100 mM NaCl, 0.02% Tween20
Reconstitution
Reconstitute with 100 µl sterile water.
Storage
Store lyophilized at -20°C for up to 6 months. Once reconstituted store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About TNFSF10 / TRAIL
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Popular TNFSF10 / TRAIL Proteins
Source:
E. coli
Tag:
His-GST, N-terminus
Source:
E. coli
Tag:
6His, C-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
