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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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POLB / DNA Polymerase Beta Protein (Over-Expression Lysate) - LS-G42554
Purified / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
POLB / DNA Polymerase Beta Protein (Over-Expression Lysate) - LS-G42554
E. coli Expression System
13 AA
None
Lyophilized
LS-G42554
Over-Expression Lysate Protein
POLB / DNA Polymerase Beta
This is GST-tagged recombinant POLB protein, expressed in E. coli, and supplied as a protein lysate. It is sufficient for use as a Western Blot standard and comes pre-loaded with Bromophenol blue dye.
Partiallength
E. coli
E. coli
None
Not Tested
Not Tested
Lyophilized from 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
POLB Protein, DNA pol beta Protein, Mutant DNA polymerase beta Protein, DNA polymerase beta Protein, DNA polymerase beta subunit Protein
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
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