Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Store at -20°C. Avoid freeze/thaw cycles. Store undiluted.
PMEL Protein, gp100 Protein, Melanocyte protein PMEL Protein, Me20m/me20s Protein, p100 Protein, PMEL17 Protein, Premelanosome protein Protein, SIL Protein, Silver homolog (mouse) Protein, Silver, mouse, homolog of Protein, Silver locus protein homolog Protein, ME20-M Protein, Me20-m/me20-s Protein, ME20M Protein, Melanocyte protein mel 17 Protein, Melanocyte protein Pmel 17 Protein, Silver (mouse homolog) like Protein, D12S53E Protein, ME20 Protein, Melanosomal matrix protein17 Protein, SILV Protein
PMEL / SILV / gp100 is a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes.