Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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PAL / PAM Protein (Over-Expression Lysate) - LS-G42503
This is GST-tagged recombinant PAM protein, expressed in E. coli, and supplied as a protein lysate. It is sufficient for use as a Western Blot standard and comes pre-loaded with Bromophenol blue dye.
Partiallength
E. coli
E. coli
None
Not Tested
Not Tested
Lyophilized from 0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
PAM Protein, PAL Protein, Peptidylglycine 2-hydroxylase Protein, Peptidylamidoglycolate lyase Protein, PHM Protein
Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity.
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