Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Determined by the mitogenic activity on human µmbilical vein endothelial cells and bovine aortic endothelial cells. Mitogenic activity was obtained for stimulation of 3H-thymidine incorporation and cell proliferation in a concentration range of 1.0 to 5.0 ng/ml.
Less than 0.1 ng/µg of protein.
Sterile filtered, lyophilized
Reconstitute in water to 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers
VEGFA / VEGF is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis.