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Mouse Securin / PTTG1 Protein (Recombinant His + T7) (aa2-199) - LS-G25071

Catalog Size Price
LS-G25071-10 10 µg Unavailable
LS-G25071-50 50 µg Unavailable
LS-G25071-100 100 µg Unavailable
LS-G25071-200 200 µg Unavailable

Most Popular Securin / PTTG1 Proteins

Human Securin / PTTG1 Protein (Recombinant His) - LS-G586
E. coli Expression System
222 AA
Purified / Endotoxin Level: Less than 0.5 EU/µg protein (determined by LAL method).
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Human Securin / PTTG1 Protein (Recombinant His) - LS-G20115
E. coli Expression System
Human Securin / PTTG1 Protein (Recombinant His + T7) (aa2-202) - LS-G25070
E. coli Expression System
His + T7
Mouse Securin / PTTG1 Protein (Recombinant His + T7) (aa2-199) - LS-G25071
E. coli Expression System
His + T7
Human Securin / PTTG1 Protein (Recombinant GST) - LS-G31541
Wheat Wheat Germ Extract
202 AA
12.5% SDS-PAGE of human PTTG1 stained with Coomassie Blue

100% Guaranteed
Recombinant Protein
Securin / PTTG1
25.3 kDa
aa 2-199
E. coli
E. coli
His + T7
Not Tested
Not Tested
Lyophilized from PBS, pH 7.4, 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose, Proclin300.
Store at 4°C for up to 1 month, or aliquot and store at -80°C for up to 1 year. Avoid freeze-thaw cycles.
For research use only.

About Securin / PTTG1

O95997 NM_004219 NP_004210.1

PTTG1 Protein, EAP1 Protein, Esp1-associated protein Protein, HPTTG Protein, ESP1-associated protein 1 Protein, Pituitary tumor-transforming 1 Protein, TUTR1 Protein, PTTG Protein, Securin Protein, Tumor-transforming protein 1 Protein

Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1.

Requested From: 
Date Requested: 5/22/2018

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