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Mouse PCSK9 Recombinant (His) Protein LS-G5043


Wt. Vol. Conc. Price
20 µg - - $445
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

Most Popular PCSK9 Proteins

Human PCSK9 Recombinant (6His,C-terminus) Protein - LS-G39338
Human Human Cells
Unpurified / Lyophilized
Human PCSK9 Recombinant (6His/HA/AVI,C-terminus) Protein - LS-G39340
Human Human Cells
Unpurified / Lyophilized
Human PCSK9 Recombinant (6His,C-terminus) Protein - LS-G39343
Human Human Cells
Unpurified / Lyophilized

100% Guaranteed 100% Guaranteed
Recombinant Protein
72 kDa. DTT-reduced protein migrates as 20 kDa and 64 kDa due to glycosylation
HEK 293 Cells
Greater than 97% by SDS-PAGE
Measured by its binding ability in a functional ELISA Immobilized mouse PCSK9 at 10 µg/ml (100 µl/well) can bind biotinylated rhLDLR. The EC50 of biotinylated human LDLR is 0.1 µg/ml.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from PBS, pH 7.4, 5-8% mannitol or trehalose
Centrifuge the vial before opening. Reconstitute in sterile PBS, pH 7.4 to 100 µg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, store at -20°C.
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About PCSK9

Q8NBP7 NM_174936 NP_777596.2

PCSK9 Protein, FH3 Protein, HCHOLA3 Protein, LDLCQ1 Protein, NARC-1 Protein, Proprotein convertase 9 Protein, NARC1 Protein, PC9 Protein

Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments. Acts via a non-proteolytic mechanism to enhance the degradation of the hepatic LDLR through a clathrin LDLRAP1/ARH-mediated pathway.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Requested From: United States
Date Requested: 10/28/2016

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