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Mouse MDM2 Recombinant (His) Protein LS-G23022

Ordering

Wt. Vol. Conc. Price
50 µg - - $275
200 µg - - $475
500 µg - - $785
1000 µg - - $1,245
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Alternate Expression Systems of this Protein

LS-G20960 E. coli

Most Popular MDM2 Proteins

Mouse MDM2 Recombinant (His) Protein - LS-G20960
E. coli Expression System
His
Unpurified / Lyophilized
Mouse MDM2 Recombinant (His) Protein - LS-G23022
Yeast Expression System
His
Unpurified / Lyophilized
Human MDM2 Recombinant (His + T7) Protein - LS-G25788
E. coli Expression System
His + T7
Unpurified

100% Guaranteed 100% Guaranteed
LS-G23022
Recombinant Protein
MDM2
Mouse
56.5 kD Full Length
aa 1-489
MCNTNMSVST EGAASTSQIP ASEQETLVRP KPLLLKLLKS
VGAQNDTYTM KEIIFYIGQY IMTKRLYDEK QQHIVYCSND
LLGDVFGVPS FSVKEHRKIY AMIYRNLVAV SQQDSGTSLS
ESRRQPEGGS DLKDPLQAPP EEKPSSSDLI SRLSTSSRRR
SISETEENTD ELPGERHRKR RRSLSFDPSL GLCELREMCS
GGSSSSSSSS SESTETPSHQ DLDDGVSEHS GDCLDQDSVS
DQFSVEFEVE SLDSEDYSLS DEGHELSDED DEVYRVTVYQ
TGESDTDSFE GDPEISLADY WKCTSCNEMN PPLPSHCKRC
WTLRENWLPD DKGKDKVEIS EKAKLENSAQ AEEGLDVPDG
KKLTENDAKE PCAEEDSEEK AEQTPLSQES DDYSQPSTSS
SIVYSSQESV KELKEETQDK DESVESSFSL NAIEPCVICQ
GRPKNGCIVH GKTGHLMSCF TCAKKLKKRN KPCPVCRQPI
QMIVLTYFN
Yeast
Yeast
His
20 mM Tris, pH 8.0, 500 mM NaCl, 50% glycerol
Long term: -80°C; Short term: -20°C. Avoid freeze-thaw cycles.
For research use only.

About MDM2

Q00987 NM_002392 NP_002383.2

MDM2 Protein, ACTFS Protein, Double minute 2 protein Protein, Hdm2 Protein, MDM2 variant FB30 Protein, HDMX Protein, Oncoprotein Mdm2 Protein, p53-binding protein Mdm2 Protein, MDM2 variant FB28 Protein

E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome. Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Also acts as a ubiquitin ligase E3 toward itself and ARRB1. Permits the nuclear export of p53/TP53. Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.

Requested From: United States
Date Requested: 12/4/2016

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