Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GCKR, also known as KHS for kinase homologous to SPS1/Ste20, is a KHS protein kinase. GCKR is an upstream activator of the stress-activated protein kinase (SAPK) signaling pathway, and its activity has been shown to increase in response to tumor necrosis factor (TNF), TNF receptor-associated factor 2 (TRAF2) and UV light. In primary B cells, GCKR has been shown to be activated by CD40.