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Mouse IL1RN Protein (Recombinant) (Arg27-Gln178) - LS-G40077
Purified / Lyophilized / Biologically Active / Animal-Free / Endotoxin Level: Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
LS-G40077
Recombinant Protein
IL1RN
Mouse
17.5kD
Recombinant Mouse Interleukin-1 Receptor Antagonist Protein is produced by our E. coli expression system and the target gene encoding Arg27-Gln178 is expressed.
Arg27-Gln178
MRPSGKRPCK
MQAFRIWDTN
QKTFYLRNNQ
LIAGYLQGPN
IKLEEKIDMV
PIDLHSVFLG
IHGGKLCLSC
AKSGDDIKLQ
LEEVNITDLS
KNKEEDKRFT
FIRSEKGPTT
SFESAACPGW
FLCTTLEADR
PVSLTNTPEE
PLIVTKFYFQ
EDQ
E. coli
E. coli
None
Greater than 95% by SDS-PAGE
Not Tested
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from 0.2 µm filtered 20 mM PB, pH 7.4, 150 mM NaCl.
Lyophilized protein should be stored at less than -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at less than -20°C for 3 months.
IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.
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