IL11 Protein LS-G23743 is Recombinant Mouse IL11 in E. coli It is biologically active and is low in endotoxin Less than 1.0 EU/µg protein (determined by LAL method)..
Predicted Molecular Weight
Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Ralpha (IL-11Ra) receptor to activate JAK downstream signaling. This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
Greater than 95% by SDS-PAGE
Tested using: B9 cell proliferation. ED50 less than or equal to 250 ng/mL (greater than or equal to 4.0 x 10^3 units/mg). In addition to the acceptance criteria, this product has been tested with the following assay: T-11 proliferation (ED50 less than or equal to 2.5 ng/mL and greater than or equal to 4.0 x 10^5 units/mg).
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitute in sterile water to 0.1 mg/ml
Store at -20°C to -80°C for up to 1 year. Store at 4°C for up to 1 month or up to 3 months at -20°C to -80°C after reconstitution.
For research use only.