LSBio The Immunohistochemistry Antibody Company
  • Antibodies
  • All Antibodies
  • Primary Antibodies
  • Secondary Antibodies
  • IHC-plus Antibodies
  • Isotype Control Antibodies
  • ELISA Kits
  • All ELISA Kits
  • Traditional ELISA Kits
  • Cell-Based ELISA Kits
  • DNA-Binding ELISA Kits
  • Phospho-Specific ELISA Kits
  • ELISA Development Kits
  • Chemiluminescent CLIA Kits
  • Proteins
  • All Proteins
  • Recombinant Proteins
  • Native Proteins
  • Over-expression Lysates
  • Cell and Tissue Lysates
  • Bio-active Proteins
  • Animal-free Proteins
  • Synthetic Peptides
  • Immunohistochemistry
  • Comprehensive IHC Reports
  • Custom IHC Services
  • TCR Screening Services
  • IHC-plus Antibodies
  • Immunohistochemistry Services

  • Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

  • TCR Screening Services

  • Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Have a question?
  • Purchasing
  • Product Ordering Terms and Conditions
  • Holiday Schedule
  • About the LSBio Guarantee
  • About Our Rewards Program
  • Reference Material
  • About LSBio (LifeSpan BioSciences Inc.)
  • About Our 2-million Specimen Tissue Bank
  • About Our IHC Validation Process
  • About Our IHC-plus™ Immunohistochemistry Protocol
  • Protocols
  • Secure Logins
  • Login to Our Secure FTP Site
  • Login to Our IHC Database
Contact Us

2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)
How to Buy - Details about how to buy our products. - To submit a new order. - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues. - To request technical information requests about an LSBio product or its application. - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Quick Order ▾
View Cart

Mouse FGF23 Recombinant (Human IgG1 Fc) Protein (aa1-251) - LS-G3815


Wt. Vol. Conc. Price
10 µg - - Unavailable
50 µg - - Unavailable

Most Popular FGF23 Proteins

Human FGF23 Recombinant Protein - LS-G51
E. coli Expression System
228 AA
Purified / Lyophilized / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human FGF23 Recombinant (Human IgG1 Fc) Protein (aa1-251) - LS-G3801
Human HEK 293 Cells
Human IgG1 Fc
Purified / Biologically Active / Endotoxin Level: Less than 0.1 EU/µg protein (determined by LAL method).
Functional Assay Image
Mouse FGF23 Recombinant (Human IgG1 Fc) Protein (aa1-251) - LS-G3815
Human HEK 293 Cells
Human IgG1 Fc
Purified / Biologically Active / Endotoxin Level: Less than 0.1 EU/µg protein (determined by LAL method).
Functional Assay Image
Human FGF23 Recombinant Protein - LS-G4938
E. coli Expression System
228 AA
Purified / Lyophilized / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Rat FGF23 Recombinant (His) Protein (aa25-251) - LS-G20738
E. coli Expression System
227 AA

100% Guaranteed 100% Guaranteed
Recombinant Protein
~50kDa (SDS-PAGE, full-length) FGF23 is cleaved between arg179 and ser 180 (~40kDa).
Signal peptide and mouse FGF-23 (aa 1-251) are fused at the C-terminus to the Fc portion of human IgG1.
aa 1-251
HEK 293 Cells
Human IgG1 Fc
Greater than 90% by SDS-PAGE
Activates ERK and FRS2alpha phosphorylation in Klotho expressing cells.
Less than 0.1 EU/µg protein (determined by LAL method).
Lyophilized from PBS.
Store at +4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid repeat freeze-thaw cycles.
For research use only.

About FGF23

Q9GZV9 NM_020638 NP_065689.1

FGF23 Protein, ADHR Protein, Fibroblast growth factor 23 Protein, FGF-23 Protein, HYPF Protein, Phosphatonin Protein, PHPTC Protein, HPDR2 Protein

FGF23 is a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR).

Functional Assay

Functional Assay
ERK and FRS2alpha phosphorylation induced by FGF-23 in Klotho expressing cells. Klotho expressing HEK 293EBNA cells were serum starved for 16 hours and then stimulated with mFGF-23-Fc (positive control) for 10 minutes, respectively. Antibodies against pFRS2alpha, pERK1/2 and total ERK1/2 were used for immunoblotting. Lane 1: Mock (non-treated) Lane 2: Klotho + mFGF23-Fc 1ng/ml Lane 3: Klotho + mFGF23-Fc 10ng/ml Lane 4: Klotho + mFGF23-Fc 100ng/ml Lane 5: Klotho + mFGF23-Fc 500ng/ml Lane 6: Klotho + mFGF23-Fc 1000ng/ml Lane 7: Klotho + 100ng/ml FGF-b

Requested From: 
Date Requested: 4/23/2017

Get Social With Us! Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2017 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy
Catalog Number