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Mouse DLL1 Recombinant (Human IgG1 Fc) Protein LS-G3831


Wt. Vol. Conc. Price
10 µg - - $285
50 µg - - $395
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

Most Popular DLL1 Proteins

Human DLL1 Recombinant (Human IgG1 Fc) Protein - LS-G3808
Hamster-Chinese CHO Cells
Human IgG1 Fc
Unpurified / Endotoxin Level: Less than 0.01 EU/µg protein (determined by LAL method).
Functional Assay Image
Human DLL1 Recombinant Protein - LS-G4920
Human HEK 293 Cells
Unpurified / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human DLL1 Protein - LS-G50068

100% Guaranteed 100% Guaranteed
Recombinant Protein
~100kDa (SDS-PAGE)
Signal peptide and extracellular domain of mouse DLL1 (aa 1-545) is fused at the C-terminus to the Fc portion of human IgG1.
aa 1-545
HEK 293 Cells
Human IgG1 Fc
Greater than 90% by SDS-PAGE
Inhibits adipogenesis of 3T3L-1 cells. Induces Hes-1 in 3T3L-1 cells.
Less than 0.1 EU/µg protein (determined by LAL method).
Store at +4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid repeat freeze-thaw cycles.
For research use only.

About DLL1

O00548 NM_005618 NP_005609.3

DLL1 Protein, Delta-like 1 (Drosophila) Protein, Delta (Drosophila)-like 1 Protein, Drosophila Delta homolog 1 Protein, Delta-like protein 1 Protein, Delta1 Protein, H-Delta-1 Protein, DL1 Protein, Npa Protein

Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

Functional Assay

Functional Assay
Adipogenesis inhibition. Macroscopic pictures.

Functional Assay

Functional Assay
Adipogenesis inhibition of 3T3L1 cells. 3T3L1 cells were maintained in DMEM, supplemented with 10% fetal bovine serum, penicilin-streptomycin. Adipogenesis was initiated by adding 1 uM Dexamethasone, 0.5mM IBMX, 10 ug/m lnsulin (day 0) until day 2. The medium was replaced every 2 days with new medium containing insulin in the presence or absence of 5 ug/ml mDLL1-Fc and hCD137-Fc (Fc control). Staining with Oil Red O was typically performed on day 7. Cells were washed twice with PBS, fixed with 3.7% formalin, and stained with 0.5% filtered Oil Red O in propylene glycol.

Functional Assay

Functional Assay
Induction of Hes-1 with the treatment of recombinant mouse DLL1-Fc (Prod. No. AG-40A-0148). A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5mg/ml of mouse DLL1-Fc as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-mouse Hes1 or GAPDH. Lane 1: mDLL1 (Fc protein), 0 minutes Lane 2: mDLL1 (Fc protein), 10 minutes Lane 3: mDLL1 (Fc protein), 30 minutes Lane 4: mDLL1 (Fc protein), 1 hours Lane 5: mDLL1 (Fc protein), 2 hours Lane 6: mDLL1 (Fc protein), 4 hours Lane 7: mDLL1 (Fc protein), 8 hours Lane 8: mDLL1 (Fc protein), 24 hours

Requested From: United States
Date Requested: 10/24/2016

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