Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ED50 1-3 nM as determined by enzyme release assay of myeloperoxidase
Less than 0.1 ng/µg of protein.
Sterile filtered, lyophilized
Reconstitute in ice-cold water containing 2.5 mg/ml BSA to 1.0 mg/ml. The solution should be aliquoted and immediately stored at -70°C for future use. Freeze/thaw will result in some loss of activity.
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.
About Complement C5a
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved into C5a and C5b. C5a plays an important role in chemotaxis. C5b forms the first part of the complement membrane attack complex. Deficiency is thought to cause Leiner's disease.