Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ANGPTL4 Protein, Angiopoietin-like 4 Protein, Angiopoietin-related protein 4 Protein, Angiopoietin-like protein 4 Protein, Fasting-induced adipose factor Protein, NL2 Protein, PGAR Protein, Pp1158 Protein, ARP4 Protein, FIAF Protein, HFARP Protein
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity.
ERK phosphorylation induced by hANGPTL4 in THP-1 cells. THP-1 monocyte cells were serum starved for 16 hours and then stimulated with ANGPTL4 (mouse) (rec.) (500ng/ml) for 1, 2 and 3 hours, respectively. Antibodies against pERK1/2 and total ERK1/2 were used for immunoblotting.