Mouse Activin A Protein (Recombinant) (aa309-424) - LS-G23705
Predicted Molecular Weight
Activin A comes as a dimer having a 117/234 amino acid chain. Activin A is a member of the transforming growth factor beta (TGF-ß) family of proteins and functions to stimulate follicle-stimulating hormone (FSH) secretion. Activins are produced in many tissue types including the skin, gonads, lungs, and pituitary gland. Activins interact with receptor type I and type II serine/threonine protein kinases, to activate SMAD signaling and regulate diverse cellular functions, such as cell proliferation, differentiation, wound healing, apoptosis, and metabolism. Activin A is a homodimer comprised of two activin ßA chains. Cleavage of the N-terminal propeptide renders the activin protein biologically active. Mouse activin A shares 100% amino acid sequence identity with human, rat, porcine, bovine, and feline activin A proteins. This product is produced with no animal or human origin raw products. All processing and handling employs animal free equipment and animal free protocols.
aa 309-424 of Q04998
Greater than 95% by SDS-PAGE
Tested using: Cytotoxicity of MPC-11 cells to an acceptance criteria of: 10 ng/mL and 1 x 10^5 units/mg
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Reconstitute in sterile water to 0.1 mg/ml
Store at -20°C to -80°C for up to 1 year. Store at 4°C for up to 1 month or up to 3 months at -20°C to -80°C after reconstitution.
For research use only.