Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human ZBTB17 / MIZ-1 Protein (Recombinant 6His,N-terminus) (Met1-Ala188) - LS-G38769
E. coli Expression System
Purified / Lyophilized / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
ZBTB17 / MIZ-1
Recombinant Human Zinc Finger and BTB Domain-Containing Protein 17 is produced by our E. coli expression system and the target gene encoding Met1-Ala188 is expressed with a 6His tag at the N-terminus.
Greater than 95% by SDS-PAGE
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from 0.2 µm filtered 20 mM PB, pH 7.25, 150 mM NaCl.
Lyophilized protein should be stored at less than -20°C. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at less than -20°C for 3 months.
ZBTB17 Protein, MIZ-1 Protein, MIZ1 Protein, Zinc finger protein 151 Protein, ZNF60 Protein, PHZ-67 Protein, Zinc finger protein 60 Protein, ZNF151 Protein
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription.