Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
UBE2I Protein, C358B7.1 Protein, SUMO-conjugating enzyme UBC9 Protein, UBC9 Protein, SUMO-protein ligase Protein, UBCE9 Protein, Ubiquitin carrier protein 9 Protein, Ubiquitin carrier protein I Protein, Ubiquitin-protein ligase I Protein, p18 Protein, SUMO-1-protein ligase Protein, Ubiquitin conjugating enzyme 9 Protein, Ubiquitin-protein ligase E2I Protein
Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'.