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Human TSTA3 / GDP-L-Fucose Synthase Protein (Recombinant GST) (Full Length) - LS-G22080
TSTA3 Protein, 3-5 epimerase/4-reductase Protein, FX Protein, GDP-L-fucose synthase Protein, SDR4E1 Protein, p35B Protein, Protein FX Protein
Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.