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Human TREX1 Recombinant (His + T7) Protein - LS-G25113

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Wt. Vol. Conc. Price
10 µg - - Unavailable
50 µg - - Unavailable
100 µg - - Unavailable

Most Popular TREX1 Proteins

Human TREX1 Recombinant (His + T7) Protein - LS-G25113
E. coli Expression System
His + T7
Unpurified
Human TREX1 Recombinant (GST) Protein - LS-G32596
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G25113
Recombinant Protein
TREX1
Human
42.2 kDa
E. coli
E. coli
His + T7
Lyophilized from PBS, pH 7.4, 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose, Proclin300.
Store at +4°C for up to 1 month, or aliquot and store at -80°C for up to 12 months. Avoid repeat freeze-thaw cycles.
For research use only.

About TREX1

Q9NSU2 NM_016381 AAK07613.1

TREX1 Protein, 3 repair exonuclease 1 Protein, 3-5 exonuclease TREX1 Protein, Aicardi-Goutieres syndrome 1 Protein, AGS1 Protein, CRV Protein, Deoxyribonuclease III Protein, DNase III Protein, HERNS Protein, DRN3 Protein

Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini. Prevents cell-intrinsic initiation of autoimmunity. Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements. Unless degraded, these DNA fragments accumulate in the cytosol and activate the IFN-stimulatory DNA (ISD) response and innate immune signaling.

Requested From: 
Date Requested: 3/29/2017

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