Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TREM1 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 180 amino acids fragment (21-200) corresponding to mature soluble extracellular domain fragment of TREM-1, having a total molecular mass of 24.76kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The TREM1 is purified by proprietary chromatographic techniques.
Greater than 95% by SDS-PAGE
10 mM Tris-HCl, pH 8, 10 mM NaCl, 50% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock.