Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TRAF3IP2 Protein, C6orf2 Protein, C6orf4 Protein, C6orf5 Protein, CIKS Protein, DKFZP586G0522 Protein, Connection to IKK and SAPK/JNK Protein, ACT1 Protein, Adapter protein CIKS Protein, NFkB-activating protein ACT1 Protein, PSORS13 Protein, TRAF3-interacting protein 2 Protein, C6orf6 Protein, TRAF3 interacting protein 2 Protein
Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB associates with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKa, IKKb, and IKKg.