Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TPSG1 Protein, Mast cell protease II Protein, Mast cell tryptase Protein, Pituitary tryptase Protein, Skin tryptase Protein, Lung tryptase Protein, TrpA Protein, Tryptase gamma I Protein, Transmembrane tryptase Protein, Tryptase gamma Protein, Tryptase gamma 1 Protein, PRSS31 Protein, TMT Protein, Gamma I Protein, Gamma II Protein, Serine protease 31 Protein, Tryptase gamma II Protein
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified.