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Human TNFRSF10B / Killer / DR5 Protein (Met1-Ser177) - LS-G49350

Catalog Size Price
LS-G49350-100 100 µg Unavailable
LS-G49350-200 200 µg Unavailable

Most Popular TNFRSF10B / Killer / DR5 Proteins

Human TNFRSF10B / Killer / DR5 Protein (Recombinant) - LS-G349
E. coli Expression System
133 AA
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein (less than 1EU/µg).
Human TNFRSF10B / Killer / DR5 Protein (Recombinant Human IgG1 Fc) (aa52-212) - LS-G3907
Human HEK 293 Cells
Human IgG1 Fc
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.01 EU/µg protein (determined by LAL method).
Human TNFRSF10B / Killer / DR5 Protein (Recombinant) - LS-G4471
E. coli Expression System
None
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 0.1 ng/µg of protein.
Human TNFRSF10B / Killer / DR5 Protein (Recombinant His) - LS-G5225
Human HEK 293 Cells
His
Purified / Lyophilized / Biologically Active / Endotoxin Level: Less than 1.0 EU/µg protein (determined by LAL method).
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
TNFRSF10B / Killer / DR5 Protein (Recombinant GST) - LS-G42956
E. coli Expression System
GST
Lyophilized

100% Guaranteed
LS-G49350
TNFRSF10B / Killer / DR5
Human
Met 1-Ser 177
HEK 293 Cells
Human
None
Greater than 95% by SDS-PAGE
1. Immobilized human TNFSF10 at 10 µg/ml (100 µl/well) can bind mouse TNFRSF10B-Fch, The EC50 of mouse TNFRSF10B-Fch is 0.07-0.17 µg/ml. 2. Measured by its ability to inhibit TRAIL-mediated cytotoxicity using L-929 mouse fibroblast cells treated with TRAIL. The ED50 for this effect is typically 20-80 ng/ml in the presence of 20 ng/ml Recombinant Human TRAIL/TNFSF10.
Less than 1.0 EU/µg protein (determined by LAL method).
Lyophilized from sterile PBS, pH 7.4
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
For research use only.

About TNFRSF10B / Killer / DR5

O14763 NM_147187 Q6FH58

TNFRSF10B Protein, Cytotoxic TRAIL receptor-2 Protein, CD262 antigen Protein, DR5 Protein, Death receptor 5 Protein, KILLER Protein, TRAIL-R2 Protein, TRICK2B Protein, TRAILR2 Protein, TRICK2A Protein, TRICKB Protein, TRICK2 Protein, CD262 Protein, Fas-like protein Protein, TRAIL receptor 2 Protein, ZTNFR9 Protein

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. TRAIL/Apo2L is a new member of the TNF family. DR4 was recently identified as the receptor for TRAIL. A novel death domain containing receptor for TRAIL was more recently identified and designated DR5, Apo2, TRAIL-R2, TRICK2, or KILLER by several groups independently.

Requested From: 
Date Requested: 10/16/2017

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