Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
THRSP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids (1-146 a.a.) and having a molecular mass of 18.9kDa.THRSP is fused to a 23 amino acid His-tag at N-terminus and purified by proprietary chromatographic techniques.
Greater than 90% by SDS-PAGE
20 mM Tris-HCl, pH 8.0, 20 mM NaCl, 10% glycerol.
Store lyophilized at 4°C. Once reconstituted, aliquot and store at -20°C. Avoid freeze-thaw cycles.
THRSP Protein, Lpgp Protein, Lipogenic protein 1 Protein, S14 Protein, SPOT14 Protein, THRP Protein, SPOT14 homolog Protein, LPGP1 Protein, Spot 14 protein Protein, Thyroid hormone responsive Protein
S14 (Thyroid Hormone Inducible Hepatic Protein) is a nuclear protein communicates the status of dietary fuels and fuel-related hormones to genes required for long-chain fatty acid synthesis. In mammary glands S14 is important for both epithelial proliferation and milk fat production. High expression of S14 in primary invasive breast cancer is predicative of recurrence. S14 also medicates the induction of lipogenesis by protestin in breast cancer cells and accelerates their growth.