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Human TFPI / LACI Protein LS-G51369


Wt. Vol. Conc. Price
10 µg - - $335
20 µg - - $455
Inquire for larger quantities
LSBio (Direct) LSBio (Direct)

Most Popular TFPI / LACI Proteins

Human TFPI / LACI Recombinant (His) Protein - LS-G19407
E. coli Expression System
Unpurified / Lyophilized
Human TFPI / LACI Recombinant (GST) Protein - LS-G22356
E. coli Expression System
Unpurified / Lyophilized
Rabbit TFPI / LACI Recombinant (His) Protein - LS-G23160
Yeast Expression System
Unpurified / Lyophilized

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Met 1-Lys 289
Greater than 97% by SDS-PAGE
Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Anaspec, Catalog # 27114). The IC50 value is < 0.5 nM, as measured in 100µL reaction mixture containing 1.25 ng trypsin (Sigma, Catalog # T4799), 10 µM substrate, 50 mM Tris, 10 mM CaCl2 , 0.15 M NaCl, 0.05% Brij 35, pH 7.5.
Lyophilized PBS, pH 7.4
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
For research use only.


P10646 NM_006287 NP_006278.1

TFPI Protein, Anti-convertin Protein, Extrinsic pathway inhibitor Protein, EPI Protein, LACI Protein, TFI Protein, TFPI1 Protein

TFPI / LACI is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop.

Requested From: United States
Date Requested: 10/26/2016

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