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Human TCF7L2 / TCG4 Recombinant (GST) Protein LS-G30648

Ordering

Wt. Vol. Conc. Price
2 µg - - $375
Inquire for larger quantities
LSBio (USA Sales Only) LSBio (USA Sales Only)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TCF7L2 / TCG4 Proteins

Human TCF7L2 / TCG4 Recombinant (GST) Protein - LS-G30648
Wheat Wheat Germ Extract
GST
Unpurified / Lyophilized
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

100% Guaranteed 100% Guaranteed
LS-G30648
Recombinant Protein
TCF7L2 / TCG4
Human
75.79 kDa
MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD
LADVKSSLVN ESETNQNSSS DSEAERRPPP RSESFRDKSR
ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI
VSNKVPVVQH PHHVHPLTPL ITYSNEHFTP GNPPPHLPAD
VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWQGQP
VYPITTGGFR HPYPTALTVN ASMSRFPPHM VPPHHTLHTT
GIPHPAIVTP TVKQESSQSD VGSLHSSKHQ DSKKEEEKKK
PHIKKPPNAF MLYMKEMRAK VVAECTLKES AAINQILGRR
WHALSREEQA KYYELARKER QLHMQLYPGW SARDNYGKKK
KRKRDKQPGE TNEHSECFLN PCLSLPPITG EKKSAFATYK
VKAAASAHPL QMEAY
Wheat Germ Extract
Wheat
GST
Glutathione Sepharose
50 mM Tris-HCl, pH 8.0, 10 mM reduced glutathione
Store at -80°C. Avoid freeze-thaw cycles.
For research use only.

About TCF7L2 / TCG4

Q9NQB0 NM_030756 NP_110383.2

TCF7L2 Protein, HMG box transcription factor 4 Protein, HTCF-4 Protein, T-cell factor-4 variant X2 Protein, T-cell factor 4 Protein, Transcription factor 7-like 2 Protein, TCF-4 Protein

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1.

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis

Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis
12.5% SDS-PAGE of human TCF7L2 stained with Coomassie Blue
 

Requested From: United States
Date Requested: 12/4/2016

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